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Author Topic: Subcutaneous Adequan injections  (Read 9809 times)
Lisa
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« on: January 19, 2010, 09:27:40 PM »

At Artax's last vet visit, I was informed that new studies have shown Adequan to be just as effective when administered subcutaneously as intramuscularly, and it doesn't matter where it's injected, when previously it was advised to give it in the muscle as close to the painful areas as possible.  Has anyone heard this or injected Adequan subcutaneously?  Artax gets it monthly and his last, on the 16th, I did subcutaneously in his shoulder area.  His hips seem to bother him most and I'd been injecting his thigh muscles, alternating legs each month.  So far so good, no signs that it's not working as well as the IM method though it's too early to tell yet.
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« Reply #1 on: January 20, 2010, 06:30:02 AM »

That is how I ginject Goofy...I do not give in the muscle.  I lift his skin, it makes an indentation, I stick needle in, draw back to make sure I haven't hit a blood vessel, and if ok inject.  I also give in shoulder are or in the butt...just depends in what positon he is in.
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Lisa
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« Reply #2 on: January 20, 2010, 03:36:19 PM »

Interesting.  You've always injected it subcutaneously?  I was instructed to do it IM until the last vet visit.  It's given IM in horses, and the bottles of it I have say "FOR INTRAMUSCULAR USE IN DOGS" with nothing about subcutaneous use.

It's good to know it will work subcutaneously too, less painful for the dogs.   thumbsup
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« Reply #3 on: January 20, 2010, 03:40:26 PM »

What exactly does the adequan do?
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Vicky
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« Reply #4 on: January 20, 2010, 04:35:03 PM »

Adequan is like joint lubrication, and from what I've seen in my dogs and others is a very effective, safe treatment for arthritis, much better than anything else I've tried.  It helped Zaynah a lot, Artax's arthritis is not nearly as severe as hers was but he used to limp occasionally and not get around quite as well but since I started him on Adequan he hasn't taken a lame step, is more active and runs faster.  I'm planning to put all my dogs on it once they reach middle age or so, since it's so safe with few possible negative side effects.

From Adequan's website (http://www.adequancanine.us/about/en/product_description.shtml):

Quote
Adequan® Canine (polysulfated glycosaminoglycan) is a prescription, water-based, intramuscular, polysulfated glycosaminoglycan (PSGAG) that helps prevent the cartilage in your dog’s joint from wearing away. It helps keep the cartilage healthy and intact, so that the bone in the joint cannot touch other bones. No other drug for arthritis can do that.

Adequan® Canine (polysulfated glycosaminoglycan) is administered two times a week for four weeks. The drug is injected intramuscularly to ensure it reaches the critical parts of the joint. It goes to work in the joint in about two hours and stays in the joint for about three days.  With Adequan® Canine you should see signs of improvement within four weeks. Your dog may begin to act like the playful, active dog you remember.
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Artax, male Retriever mix, 11/1/99
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« Reply #5 on: January 20, 2010, 06:27:09 PM »

In Goofy's case it helped him move!  He barely could run let alone walk and if he did get about he went lame and was in pain. I started him right after the boxer bash...I did a week of 2 shots, then 2 times a week for the next 2 weeks, then one time a week for another 2 weeks and now he gets them once a month to 6 weeks depending on how he is doing.  He will never have the mobility that the others have due to the abuse he suffered and the possibility that he was hit by a car as a pup and not treated (something Scott and the HV think is a possibility too since his skeleton (spine, pelvis & hips) are all messed up and have severe arty. 
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« Reply #6 on: January 20, 2010, 10:06:53 PM »

Lucy's injections were given intramuscular, and she developed a weird patch of skin on one side. Dr. Morgan alternated sides for each injection, and Lucy's left side still appears to have patchy hair loss and the skin itself is sort of dry and almost seems scabby. It doesn't seem to bother her, so I'm not going to get too concerned about it. But it still seems kind of weird. Huh?
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Amber

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« Reply #7 on: January 21, 2010, 06:36:17 AM »

Goofy has been on these for 2.5 years and has no ill effects...all his shots have been given sub-q, but I just had his script refilled by Scott who didn't originally prescribe the Adequan to him and the instructions say intramuscular...I will continue giving sub-q since they are less painful that way.

Lisa & Amber, how much do you give per shot?  A vial lasts me 3 shots with a little left (I do eek that out tho to use...takes 3 vials to make a shot tho) Goofy gets 1.6 ml per shot.
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« Reply #8 on: January 21, 2010, 09:22:12 AM »

How much does it cost?  I wonder if this would be a viable option for Zeus instead of all the pills  Huh?

I am taking him to a new Vet on Saturday and I was thinking of talking to her about it, but I I wanna go in knowing all I can.
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Vicky
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« Reply #9 on: January 21, 2010, 09:52:03 AM »

About 45 to 50 a vial.  Shots go by weight so 3 shots/vial with about .3 ml left per bottle, for Goofy @ 90#...it would be alot more for Zeus...I usually get 2 vials and they last about 6 months.  Initially when you start it is VERY costly tho, with shots weekly and then every2 weeks etc...
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« Reply #10 on: January 21, 2010, 09:58:13 AM »

About 45 to 50 a vial.  Shots go by weight so 3 shots/vial with about .3 ml left per bottle, for Goofy @ 90#...it would be alot more for Zeus...I usually get 2 vials and they last about 6 months.  Initially when you start it is VERY costly tho, with shots weekly and then every2 weeks etc...
ugh.  That is spendy.  If there was a guarantee it would work, I would do it.  But I don't even think it would work for him.  I am glad Goofy is getting relief and mobility.  How old is he now?  Zeus will be 8 on May 15th.  I can't believe we have gotten him for this long!  Kinda proves the Vets don't know everything! 
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Vicky
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« Reply #11 on: January 21, 2010, 10:56:44 AM »

I don't know how much Lucy was given, I had the vet do it. And she recommended after the initial injections that we could go to an oral supplement, Dasuquin. She said they do pretty much the same thing, but the Adequan is much stronger. I really do not know if Lucy benefited from the injections, as her torn CCL in the left leg keeps her limping periodically regardless of how well lubricated her joint is. But I can say that there is never any sign of soreness in the right knee, which has already had the CCL repaired and is far more arthritic than the left knee.
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Amber

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« Reply #12 on: January 21, 2010, 11:41:36 AM »

It took a while to see any change in G-Man...my dad's westie gets shots...as needed, so it really is not benefiting him all that much. From what I have been told, they need to be on forever toget the benefit from it.

Vicky Goofy will be 8 April 14th (Fingers Crossed)
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Lisa
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« Reply #13 on: January 21, 2010, 05:41:42 PM »

I was told the dosage is 0.02cc per pound of dog body weight.  So a 60 pound dog would get 1.2cc, 70 pounds 1.4cc, etc.  Artax currently weighs about 75 pounds but should weigh around 70, really hard to keep weight off him despite all the exercise he gets, and I give him a little over the recommended dosage, about 1.6cc, to make three doses per 5cc bottle so I don't have to deal with combining partial bottles.

Here is the cheapest priced place I've seen it:

http://www.discountpetdrugs.com/adequan.html

They always seem to have that same "sale" price of $169.95 for four 5cc bottles. I've ordered from them several times always with fast shipping.  It's pretty expensive for the first four weeks for larger dogs but after it's tapered off to one injection per month it isn't bad, especially if it could eliminate the need for some other medications, and it doesn't carry the risks most pain medications do.  I haven't heard of an arthritic dog that it didn't help.
« Last Edit: January 21, 2010, 05:44:32 PM by Lisa » Logged

Artax, male Retriever mix, 11/1/99
Koda, CGC RN TT AD, male brindle, 10/10/08
Mukki, CGC, female fawn, 4/20/10

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« Reply #14 on: January 21, 2010, 06:03:06 PM »

Wow that is a good price!  I paid 103 for 2 plus syringes & shipping!
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Boxer Crazy Forum  |  Boxer Health  |  General Health  |  Topic: Subcutaneous Adequan injections « previous next »
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